The relationship between the spatial variation of soil total nitrogen (STN) and the natural and human environment in different climatic regions was revealed by using geographic detector model，a method of spatial counting to detect spatial variation and identify the driving factors, in Shaanxi Province. The results showed that the STN content was generally high in the south and low in the north, and presented a moderate intensity of variation in the 2020s, with an average content of 0.91g/kg. The average STN content in Qinba District was the highest (1.40g/kg), and the lowest (0.37g/kg) in Central Mongolia. On the whole, STN variation was more affected by natural factors than human factors, and influenced by the single factor of soil organic matter content (q value of 0.63~0.86) mainly, and secondly the county-level administrative divisions (q value of 0.13~0.67). Among other factors, the city-level administrative division and the duration of sunshine were more influential in Shaanxi Province, q-value both reached more than 0.50;in Qinba District and Central Mongolia District, the higher driving factor was the soil subtypes (q value of 0.22~0.30);the degree of influence of municipal administrative division was the highest (q value of 0.31) in Weihe District;the fertilizer application in Shanxi-Shaanxi-Gansu had the greatest influence (q value of 0.47);and the available phosphorus content (q value of 0.26) in the eastern Inner Mongolia was the higher driving factor on STN variation. The influence of factors was interactive on the variation of STN, the synergistic effect of the STN showed mutual enhancement or non-linear enhancement and the interaction of the two factors enhanced the influence of the single factor on STN.