The Chinese Journal of Clinical Pharmacology. 2014, (10) Core

Clinical curative effect and safety analysis of insulin glargine and acarbose treatment in elderly diabetes patientsChinese Full Text

WANG Xiao-jing;RUAN Ling-yan;ZHOU Xiao-ai;Department of Endocrinology,Yinzhou Second Hospital in Ningbo;

Abstract: Objective To study the clinical curative effect and safety analysis of insulin glargine with acarbose treatment in elderly patients with diabetes. Methods A total of 120 cases of elderly patients with diabetes were randomly divided into two groups. The 60 patients of treatment group were treated with insulin glargine and acarbose combination,and the 60 patients of the control group were treated with isophane protamine biosynthetic human insulin injection and acarbose combination. The patient monitored blood glucose levels and recorded adverse events. The therapeutic time and the daily amount of insulin were recorded of two groups of patients. The average daily blood sugar were calculated and the HbA1 c and fasting c- peptide values were detected at 3 months after treatment. Results The HbA1 c,fasting glucose,and daily average blood glucose levels were lower than before treatment. The average daily blood sugar level of treatment group was obviously lower than the control group. The therapeutic time of treatment group patients was lower than the control group patients and the dosage of insulinwaslower in treatment group than control patients usage. The nocturnal hypoglycemia and gastrointestinal reaction event occurrences of the medicine were lower thanthe control group. The fasting c- peptide levels was higher than control group after treatment. Conclusion There was a good therapeutic effect for elderly diabetes patients with insulin combination and acarbose,which can fast safe and effective control blood sugar of patients.

Keywords：

insulin glargine; acarbose; elderly diabetes patient;

DOI：
10.13699/j.cnki.1001-6821.2014.10.005
Series：
Subject：
Classification Code：
R587.1

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Clinical curative effect and safety analysis of insulin glargine and acarbose treatment in elderly diabetes patientsChinese Full Text

WANG Xiao-jing;RUAN Ling-yan;ZHOU Xiao-ai;Department of Endocrinology,Yinzhou Second Hospital in Ningbo;

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