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Chinese Journal of Hospital Pharmacy. 2014, (17) Core

Pharmacoeconomics of HP-hMG andγ-FSH for ovulation induction:A systematic reviewChinese Full Text

TANG Hui-lin;YI Zhan-miao;ZHANG Ting;ZHAI Suo-di;Department of Pharmacy,Peking University Third Hospital;

Abstract: OBJECTIVE To evaluate the cost-effectiveness of highly purified human menopausal gonadotrophin（HP-hMG）and recombinant follicle stimulating hormone（γ-FSH）for ovulation induction.METHODS PubMed,Cochrane library,CNKI and WanFang were searched to include studies which had evaluation on the cost-effectiveness of HP-hMG andγ-FSH for ovulation induction,with the published date before August 2013.According to the inclusion criteria,studies were critically evaluated.Relative data in the studies were extracted for an aggregate analysis.RESULTS Six studies,most of which were from European countries,were included.Regarded to the efficacy,no significant difference was observed on the ongoing pregnancy and clinical pregnancy rate between HP-hMG andγ-FSH,and live birth rate of HP-hMG was not inferior toγ-FSH.Results of the pharmacoeconomics analysis showed that the cost of HP-hMG was lower thanγ-FSH.CONCLUSION HP-hMG was not inferior toγ-FSH in ovulation induction and a cost-effectiveness choice.
Keywords：

recombinant follicle stimulating hormone （γ-FSH）; highly purified human menopausal gonadotrophin （HP-hMG）; ovulation induction; pharmacoeconomics; systematic review;

  • DOI：

    10.13286/j.cnki.chinhosppharmacyj.2014.17.16

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  • Subject：

  • Classification Code：

    R714.8

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