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Chinese Journal of Hospital Pharmacy. 2014, (02) Core

Investigation and analysis on the current situation of warfarin usage in patients receiving anticoagulant therapyChinese Full Text

ZHANG Zhe;LUO Meng-lin;TIAN Min;ZHANG Yi;LIU Quan-yi;Department of Pharmacy,Xinqiao Hospital of Third Military Medical University;Department of Cardiology,Xinqiao Hospital of Third Military Medical University;Department of Pharmacology,College of Pharmacy,Chongqing Medical University;

Abstract: OBJECTIVE To evaluate the usage of warfarin in anticoagulant patients and to explore the key points of anticoagulant management service.METHODS A survey of the usage of warfarin for both in-patients and out-patients was conducted from January to December 2012 using PASS system,questionnaires,and telephone interview,further to propose the key points of anticoagulant management service.RESULTS The average age of patients was 58±11.9,and the main reason taking warfarin was artificial valve replacement and atrial fibrillation.These patients took an average of 4.9 medications,with 79.2% of them taking at least 4 medications,and 51.39%taking Chinese herb.Awareness rates of coagulation index monitoring,drug interaction of warfarin,and management of bleeding caused by warfarin was 6.2%,9.7% and 12.5%,respectively.The success rate of anticoagulant therapy was 21.16% in outpatients.CONCLUSION Patients taking warfarin often took several other drugs in combination.Patients had poor knowledge of the key points of anticoagulant therapy,and low success rate in outpatient.Systematic anticoagulant management was needed to improve the safety and efficacy of anticoagulant therapy.
Keywords：

warfarin; anticoagulation management service; pharmaceutical services;

  • DOI：

    10.13286/j.cnki.chinhosppharmacyj.2014.02.13

  • Series：

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  • Classification Code：

    R452

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