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Progress in Modern Biomedicine. 2014, (29)

Effect of Sequential Enteral Nutrition on Nutritional Metabolism, Immune Function and Prognosis in Eldly Patients with Severe StrokeChinese Full Text

PENG Xu;ZHANG Zhi-bo;TAN Hong;ZHANG Dan;TANG Lu;XIAO Le;WANG Ai-min;LIANG Yong;Department of Neurology, the First Hospital Of Changsha;

Abstract: Objective: To investigate the effect of sequential enteral nutritional support on nutritional metabolism, immune function and prognosis in elderly patients with severe stroke. Methods: Ninety elderly patients with severe stroke were selected and randomly divided into three groups: SEN（sequential enteral nutrition） group, EN（enteral nutrition） group and the control group who were given normal liquid diet. To count the complication rates, indicators related to nutrition and immune were tested, and Glasgow coma score（GCS）and National Institutes of Health Stroke Scale（NIHSS） were also used at the 1st day and 14th day of hospitalization. Results:The nutritional index decreased at the 14th day after admission in all the three groups, and there was a more significant decrease in the control group（ P ＜ 0. 05）. Compared with the control group, after 14-day nutrition support, the levels of the blood total lymphocyte count（TLC）, IgA, IgM and IgG in SEN group and EN group were obviously higher, and the GCS showed significant increase while the NIHSS markedly decreased. And also the complication rate was lower in SEN group and EN group than that in control group. Conclusions:Since the nutritional conditions were deteriorated in elderly patients with severe stroke with the duration of stroke, enteral nutritional support can improve nutritional status, enhance immune function, reduce the complication rates and improve clinical prognosis. And the sequential enteral nutrition support was more effective than the enteral nutrition support.
Keywords：

Sequential enteral nutrition; Severe stroke; Immune function;

  • DOI：

    10.13241/j.cnki.pmb.2014.29.021

  • Series：

  • Subject：

  • Classification Code：

    R743.3

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