Knowledge Network Node
Progress in Modern Biomedicine. 2014, (19)

Pathogens and Drug Resistance in Patients of Severe Craniocerebral Injury Combined with Pulmonary InfectionChinese Full Text

WU Jing-fang;LI Si-rui;CHENG Xin-fu;TAN Zong-de;LIN Ai-long;People’s Liberation Army 161 Hospital;

Abstract: Objective: To observe the characteristics of pathogens and drug resistance in patients of severe craniocerebral injury combined with pulmonary infection, provide the references for clinical diagnosis and treatment. Methods: A retrospective analysis was carried on the 62 severe craniocerebral injury patients who were admitted in our hospital between February 2010 and February 2012, and the distribution of pathogens and drug sensitivity characteristics of inspection were analyzed. Results: In 62 patients with severe craniocerebral injury, pulmonary infection were found in 28 cases, the rate of pulmonary infection was 45.16%. A total of 31 strains of pathogens were isolated, including 21 strains of gram negative bacilli, accounting for 67.74%; 6 strains of gram positive coccus,accounting for 19.35%; 4 strains of fungi, accounted for 12.9%. By the analysis of drug susceptibility test, gram negative bacilli were highly sensitive to imipenem; gram positive cocci to rifampin, vancomycin, nitrofurantoin, highly sensitive, univariate analysis,tracheotomy operation history, the length of hospitalization, underlying diseases, shock, the use of respirator were risk factors of severe brain injury combined with pulmonary infection（P＜0.05）. Conclusion: Gram-negative bacilli were the main infection pathogens of severe craniocerebral injury complicated by pulmonary, with high incidence rate. It is important to apply sensitive antibiotics, according to the characteristics of pathogenic bacteria to improve the therapeutic effect.
Keywords：

Severe craniocerebral injury; Pulmonary infection; Pathogen; Drug resistance;

  • DOI：

    10.13241/j.cnki.pmb.2014.19.035

  • Series：

  • Subject：

  • Classification Code：

    R651.15

  • Mobile Reading
    Read on your phone instantly
    Step 1

    Scan QR Codes

    "Mobile CNKI-CNKI Express" App

    Step 2

    Open“CNKI Express”

    and click the scan icon in the upper left corner of the homepage.

    Step 3

    Scan QR Codes

    Read this article on your phone.

  • HTML
  • CAJ Download
  • PDF Download

Download the mobile appuse the app to scan this coderead the article.

Tips: Please download CAJViewer to view CAJ format full text.

Download: 50 Page: 3737-3739 Pagecount: 3 Size: 848K

Related Literature
  • Similar Article
  • Reader Recommendation
  • Associated Author