With the stable and efficient development of strawberry industry，the obstacle of continuous planting in greenhouse is becoming more and more serious.In this experiment，five different soil conditioners were tested，including silicon-calcium-potassium-magnesium conditioner，calcium-magnesium-phosphate conditioner，lauryl alcohol-ammonium ethoxy sulfate，mixture of natural marine extract calcium carbonate and coconut extract and polyacrylamide.The soil nutrients，enzyme activities，salt content，yield and quality of strawberries under different experimental treatments were analyzed.The results showed that silicon-calcium-potassium-magnesium was an ideal soil conditioner to improve the soil with continuous cropping obstacle of strawberry planted in greenhouse.Compared with the treatment of CK，the application of silicon-calcium-potassium-magnesium conditioner improved the soil pH value，significantly increased soil alkali hydrolyzed nitrogen，available phosphorus and available potassium，but had no significant effect on the organic matter，and it could improve soil enzyme activity to a certain extent.Compared with CK，the yield of strawberries with silicon-calcium-potassium-magnesium treatment increased by 19.5%(P<0.05)，the average weight of single fruit increased by 7.35 g(P<0.05)，soluble sugar increased by 10%～18%，titratable acid increased by 3.1%～18.3%，vitamin C increased by 1.4%～23.5%，anthocyanin increased by 0.7%～43%.In addition，compared with the control，polyacrylamide treatment tended to increase the yield of strawberry by 19.1%(P<0.05)，the average single fruit weight by 14.5 g(P<0.05)，and decrease the total water-soluble salts in soil by 11%(P<0.05)，especially the contents of SO42-，NO^3-.In order to effectively overcome the long-term continuous cropping obstacle of strawberry，it is suggested that silicon-calcium-potassium-magnesium conditioner and polyacrylamide should be combined applied.