袁克兵,张培英,杨 猛,等.2005—2020年山东省滕州市宫颈癌流行特征及经济负担研究[J].中国肿瘤,2023,32(1):20-26.
2005—2020年山东省滕州市宫颈癌流行特征及经济负担研究
Incidence, Mortality and Economic Burden of Cervical Cancer in Tengzhou City of Shandong Province from 2005 to 2020
投稿时间:2022-06-29  
DOI:10.11735/j.issn.1004-0242.2023.01.A004
中文关键词:  宫颈癌  发病  死亡  经济负担  回顾性队列研究
英文关键词:cervical cancer  incidence  mortality  economic burden  retrospective cohort study
基金项目:
作者单位
袁克兵 滕州市疾病预防控制中心 
张培英 滕州市中心人民医院 
杨 猛 滕州市疾病预防控制中心 
张 帅 滕州市疾病预防控制中心 
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中文摘要:
      摘 要:[目的] 了解滕州市2005—2020年宫颈癌发病、死亡情况及经济负担。[方法] 宫颈癌发病及死亡资料来自2005—2020年山东省慢性病监测信息管理系统,采用描述流行病学方法分析发病及死亡特征。利用信息系统查询与入户面对面方式实施2015—2020年经济负担调查,以2020年为价格基准对经济负担数据调整使其具有可比性,利用多元线性回归分析直接医疗费用影响因素。[结果] 2005—2020年宫颈癌年均粗发病率10.96/10万,中标发病率8.50/10万;粗死亡率4.89/10万,中标死亡率3.81/10万。16年间年均粗发病率上升172.75%,粗死亡率下降39.75%,发病及死亡年龄分别后移8.27岁和6.06岁,总体上呈现了发病率升高且年轻化以及死亡率下降,发病和死亡年龄后移的趋势。2015—2020年宫颈癌总经济负担城区人均中位数为209 930.87元,显著高于农村地区人均的103 596.44元(P<0.01)。直接经济负担占总经济负担的68.56%,农村地区(68.36%)显著高于城区(61.62%);自付医疗费用占比农村地区为56.68%,显著高于城区(48.06%)(P<0.01)。多元线性回归模型分析结果显示,医疗保障条件好、诊疗医院级别高、住院时间长、住院次数多、城区户籍和发病年龄大是直接医疗费用增加的正向因素。[结论] 滕州市宫颈癌发病率逐年升高且呈年轻化趋势,医疗经济负担严重且农村地区高于城区,应当继续加强宫颈癌的早诊早治措施的推广。
英文摘要:
      Abstract:[Purpose] To analyze the incidence, mortality and economic burden of cervical cancer in Tengzhou City from 2005 to 2020. [Methods] The data of cervical cancer incidence and mortality from 2005 to 2020 were collected from Shandong Chronic Disease Monitoring Information Management System. Descriptive epidemiological method was used to analyze the characteristics of morbidity and mortality. The economic burden survey was carried out by means of information system query and face-to-face approach, and the economic data was adjusted with the price benchmark of year 2020 to make it comparable, and the multiple linear regression model was used to analyze the influencing factors of direct medical expenses. [Results] From 2005 to 2020, the average annual crude incidence rate of cervical cancer in Tengzhou was 10.96/105, and the the age-standardized incidence rate by Chinese standard population was 8.50/105; the crude mortality was 4.89/105, the age-standardized mortality rate by Chinese standard population was 3.81/105. During the 16 years, the average annual crude incidence rate increased by 172.75% and the crude mortality rate decreased by 39.75%, the age of onset and death were moved back by 8.27 years and 6.06 years, respectively. From 2015 to 2020, the median number of total economic burden of cervical cancer per patient in urban areas was 209 930.87 Yuan, which was significantly higher than that in rural areas (103 596.44 Yuan) (P<0.01). The direct economic burden accounted for 68.56% of the total, and the burden in rural areas(68.36%) was significantly higher than that in urban areas (61.62%)(P<0.01). The ratio of self-paid medical expense/direct medical expense in rural areas (56.68%) were significantly higher than that in urban areas (48.06%) (P<0.01). Multiple linear regression analysis showed that good medical security conditions, high grade of medical hospital, long hospitalization time, multiple hospitalization, urban residents and older age of onset were the positive factors for the increase of direct medical costs. [Conclusion] The incidence of cervical cancer in Tengzhou City is increasing and the onset age becomes younger; the economic burden is heavier in rural areas than that in urban areas. The promotion of early diagnosis and early treatment measures of cervical cancer should be strengthened.
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